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A more important issue, by contrast, is the site's current lack of permeability.
However the lack of permeability greatly limited it from further clinical application.
Additionally, a lack of permeability in institutions' boundaries (be it from one organization to the next, from one occupation to another, from theory to praxis, from university to industry, or from family to work) places heavy biographic risks on every single scientist.
The 20-fold difference in internal and external concentrations is indicative of the lack of permeability of the C. elegans cuticle.
The latter result is most encouraging as the lack of permeability across the outer membrane of A. baumannii is a significant challenge in medicinal chemistry.
This is likely to be partially due to lack of cellular permeation (a hypothesis supported in part by lack of permeability in Caco-2 cells).
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However the major drawbacks of the conventional drug delivery system like lacking of permeability through ocular barrier and poor bioavailability of water soluble drugs have been overcome by the emergence of NSVs.
Lack of detailed permeability data often hampers the reservoir characterization efforts.
A cement-based composite system is an innovative strengthening system that shares many of the benefits of fiber reinforced polymer (FRP) systems (such as light weight, ease of installation and non-corroding) while overcoming some of the draw backs of epoxy-based FRP systems (including poor compatibility with concrete substrate, lack of vapour permeability and fire resistance).
In reality this ratio will be less as there is some direct use geothermal potential within the Carboniferous and Devonian sedimentary basins (Busby 2014), but this is difficult to quantify due to a lack of deep permeability data for the upper Palaeozoic.
This confirms previous work demonstrating the lack of membrane permeability of BS3 [27].
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