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Next, we showed that the addition of either glucose or lactate to the upper well also significantly inhibited SiHa migration (Figure 6d), thus providing a functional coupling between the lack of oxidative substrates and the migration of oxidative TCs towards glucose.
This may partly explain the lack of oxidative modification of the cysteine residue(s) in ANT.
It is possible that the lack of oxidative phosphorylation limits the production of proapoptotic superoxide.
A recent study suggested that impaired nuclear translocation of Nrf2 may underlay the lack of oxidative stress response in FRDA cells [71].
They show not only the lack of oxidative enzymes, but also the acid phosphatase reactivity and ultrastructurally the myofibrillar disorganization.
In both cell lines a lack of oxidative DNA damage was found for pristine and functionalized MWCNTs and 6(d)).
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Since RS formation in F.candida is difficult to quantify, yeast strain BY4742 (wild-type) and mutants lacking of oxidative stress-related protective enzymes were exploited as a further eukaryote model organism.
Except near redox interfaces, lack of oxidizing agents curtails oxidative pathways of S0 consumption.
Our results indicate that the HU treatment of the ∆ybeY cells does not elicit the oxidation of HFP and thus that is possible that this lack of an oxidative response is the primary physiological reason that a ∆ybeY mutant is not killed by HU.
The lack of mitochondrial oxidative activity of parasites detected by the MTT assay, suggested that peptides were leishmanicidal and trypanocidal.
One of the weaknesses of the underpinning science is the lack of validated oxidative stress biomarkers.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com