Sentence examples for lack of murine from inspiring English sources

The lack of murine orthologs of most of these genes (with the exception of STS and PRKX) and the limitations of mouse models for complex human cognitive abilities precludes identifying the causative gene by knockout models.

19 However, the limited availability of patient tissue and the lack of murine albumin-bound paclitaxel have hampered our ability to address the mechanism of action of nab-paclitaxel in human and murine PDA.

These efforts have been impeded by the lack of a survivable murine model that reliably allows investigation of the pathogenesis of pleural organization and remodeling.

This is likely due to the lack of reliable experimental murine models reproducing various aspects of C. jejuni pathogenesis [11].

Such a protocol has so far been lacking for the isolation of murine PMN.

The lack of true homology between murine and human monocyte subpopulations limit the direct application of findings in murine atheroma to that observed in human cohorts.

As shown in Figure 2B, all recombinant viruses grew with similar kinetics to the parental ECTV on BSC-1 cell monolayers, showing that lack of vCD30 or expression of murine CD30 does not affect viral replication in cell culture.

Due to lack of reliable antibodies for murine Noxa, we were unable to monitor protein levels.

While our in vitro studies support a role of OCRL in ciliary function, the lack of phenotype in the murine knockout model can be interpreted in the context of the primary cilia and polarity dysfunction (71).

Thus, these sequences seem to be completely absent in the mouse genome and the method shows high specificity for human tissues with a complete lack of positive signals for murine tissues.

Shortened transcripts of murine PTPs lacking catalytic or interaction domains by alternative splicing can act in a dominant negative manner [ 48].