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The lack of MND research in most parts of Africa can be partly blamed on the lack of adequately trained and equipped scientists conducting neuroscience research on the continent [ 42, 43].
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Two of the cases with FTLD-MND were considered to have preclinical MND since they had no documented clinical findings of MND.
Furthermore, stakeholders commented on the lack of a clear strategic plan for MNDs, with limited leadership capacity to manage the necessary multisectoral response and coordinate multiple stakeholder involvement for MNDs.
Chris, Stuart and Gemma have since founded a charity, the Broad Appeal, to raise both awareness of MND and funds for research.
Symptoms of MND are rare.
No signs of MND were detected.
Participants all had a diagnosis of MND from a neurologist with expertise in MND.
Topological parameters: D, density; MND, mean node degree; MNDSD, standard deviation of MND; MCC, mean clustering coefficient of the network.
Four patients (two with an initial clinical diagnosis of FTD MND) underwent electrophysiological studies; one individual had EMG evidence of MND, one had borderline features and two had no features of MND.
All patients in this group had FTD-MND presenting as a behavioural syndrome with features of MND supervening later in the course.
Stress-induced uptake of toxicants could take place after the onset of MND, because having a disease such as MND is likely to be highly stressful.
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CEO of Professional Science Editing for Scientists @ prosciediting.com