In mice, lack of Tbx5 and Nkx2.5 results in an hypoplastic heart and absence of looping [11], [34], indicating that lack of looping in the absence of chamber growth is conserved in mice.
Our modest performance could be attributed to our lack of advanced loop modeling capabilities or alignment optimization [49] and our reliance on single-template models.
Although miR-34a was previously shown to regulate TP53, we do not see it differentially expressed in the context of TP53 mutational status which might indicate a lack of feedback loop in this regulation.
(41)) In addition, the lack of interdomain loops in NaChBac means that functions such as inactivation by the plug formed by the loop region between domains III and IV in eukaryotic NaVs must be accomplished in another way in prokaryotic NaVs.
Reduction of these cost factors is not yet possible due to the lack of closed-loop control systems.
) Multiple reviewers liked how the game continually renewed itself with the slow introduction of new game elements, though Harry Slater of Pocket Gamer described the core gameplay as "one-note" and criticized its lack of addictive loops that keep players interested.
By simple comparison of the sequence specific assignment of WTVP6 on the H-N-HSQC spectrum shown in Fig. 1A, many of the signals could be assigned unambiguously for the short deletion construct (d1VP6, data not shown), demonstrating that the lack of this major loop did not affect the structure of core domain, even when the entire loop was removed (d2VP6, data not shown).
Despite the lack of the vertical loop, the coaster continued to hold the record as tallest and fastest wooden roller coaster in the world.
The lack of a passing loop suitable for passenger trains on the Amlwch line meant that trains could only operate every two hours.
Because of the lack of a balloon loop at Rikshospitalet, Line 18 must be operated with SL95 units, while SL79 units are used on Line 19 because the Brikeby Line does not have a high enough permitted axle load to for the SL95 units.
