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The major obstacle for the use of PAC has been the lack of demonstrating patient benefit and its level of invasiveness.
Despite the lack of demonstrating a statistically significant P, a tendency could be demonstrated with an increase in sample size.
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It was this lack of demonstrated clinical benefit, combined with the potentially severe side effects of the drug, that led the F.D.A. last year to reject the use of Avastin with Taxol or with the other chemotherapies for breast cancer.
The latest controversy to engulf the chief justice comes less than two months after an outgoing colleague, Alan Wilson, said Carmody had "lost all respect" of his peers because of his hypocrisy, his lack of demonstrated legal ability and his preference for public relations over court work.
A lack of demonstrated empathy has a significant impact on aspects of communal living for persons with Asperger syndrome.
Indeed a 2008 analysis by the Department of Corrections in New Jersey concluded, "Given the lack of demonstrated effect of Megan's Law, the researchers are hard-pressed to determine that the escalating costs are justifiable".(Source).
Lack of demonstrated ownership of land is one legal framework used to justify land evictions, but in Jakarta, there are also a variety of personal documents are officially required for citizens in order to have access to public services, apply for jobs, operate businesses, etc.
Plasma BE was measured due to the invasiveness of cerebrospinal fluid sampling, because of the lack of demonstrated utility of urine BE measurements, and due to the existence of several prior reports of plasma BE concentrations in autism.
Additionally, limits were set to the provision of physiotherapy and psychotherapy for a lack of demonstrated effectiveness.
Robust methods for serum collection and processing were not described and this could have explained the lack of demonstrated association.
We preferred generic names and no EC number, given a lack of demonstrated function for proteins in this cluster.
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