Sentence examples for lack of checkpoint from inspiring English sources

We noted that the lack of checkpoint bypass in the absence of Rad53 is in contrast to the bypass observed in Dbf4 truncation mutants.

Likewise, the normal attachment of the chromosomes to the metaphase plate and lack of checkpoint activation that monitors spindle tension [ 65] in geminin-silenced cells suggest that kinetochores are also unaffected by geminin silencing.

"I never thought to ask whether the lead banker owned shares in the other company," Victor I. Lewkow, a longtime lawyer and partner at Cleary Gottlieb Steen & Hamilton, acknowledged to a packed room matter-of-factly last Thursday, demonstrating the utter lack of checkpoints put in place during a typical merger negotiation by an often seven-figure legal team.

Allgame contributor Colin Williamson noted the game as extremely hard due to its "pixel-perfect jumps", the "sheer number of attackers and flying bullets", and a lack of checkpoints within each stage.

In contrast, the G1 fraction of doxorubicin-treated mESCs decreased dramatically from 20%to1%1%, whereas its G2 fraction increased from 11%to99%9%, indicating a lack of G1 checkpoint in mouse PSCs and accumulation of cells at the G2 checkpoint.

The lack of a checkpoint late in cytokinesis therefore is in line with the understanding of other systems.

Lack of other checkpoint proteins also affects Cdc20p turnover (data not shown and [14]), but lack of Mad3p has the most stabilising effect.

This also weakens their argument that the data indicate a lack of a checkpoint prior to release.

Indeed, lack of G1 checkpoint may allow unrepaired DNA damage to become exacerbated during subsequent replication leading eventually to cell death.

Pluripotency is also linked with cell-cycle regulation because studies in mouse ESCs (mESCs) have shown that their pluripotent status is associated with a specific cell-cycle profile characterized by a shortened G1 phase and the lack of G1 checkpoint regulation (Coronado et al., 2013; Savatier et al., 1996).

Death Row exposed GTA's infuriating lack of mission checkpoints, as you drove to AmmuNation to buy a bulletproof vest for the 17h time.