Moreover, we found that heat denaturation in the presence of 2-mercaptoethanol prior to electrophoresis does not inhibit the activities of either enzyme, suggesting a lack of the functionally important disulphide bonds in their native structure.
In general, a lack of functionally normal neutrophils in an individual may lead to infections with Staphylococcus aureus, gram-negative organisms such as Pseudomonas aeruginosa and Burkholderia cepacia, the gram-positive bacterium Nocardia asteroides, and infections with fungi and yeasts such as Aspergillus spp. and Candida spp. (Fig. 1).
Considering lack of such functionally relevant deactivation in SZ group and in false memory trials in CO, less task-induced deactivation in the prefrontal area during maintenance may have contributed to maintaining false representations.
This inherent plasticity of disordered regions, which is not evident in ordered regions, is consistent with models suggesting that the lack of a stable protein conformation might be functionally advantageous by allowing the flexibility to interact with many different targets (Dyson and Wright 2002, 2005).
That is, in situations which lack of a single dominant imperative, several alternative, and functionally equivalent management control system (MCS) designs, may arise.
To study phagocytosis, secretion and intracellular trafficking in CHM patients, we are limited by the lack of functionally relevant cell culture models pertinent to the eye, which are functionally deficient in REP-1.
Cytochrome P450 enzymes have traditionally been difficult to functionally express in E. coli due to a lack of a compatible P450 reductase[ 28].
Because of the lack of specific ligands, functionally characterizing the α1-ARs and discriminating between the three subtypes are difficult.
Because of the lack of information about functionally important domains, we sought to delete the most conserved, amino-terminal, portions of the proteins by replacing genomic sequences with a neomycin resistance cassette.
