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The most important and frequent study limitations were lack of a consecutive series of patients and biased patient selection for surgery.
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Antisense morpholino oligos are selected with 40 60% GC content, less than 37% G content, and a lack of any consecutive tri- or tetra-G nucleotide sequences.
Twenty ICUs that, for organization reasons or for lack of A(H1N1) patients, did not complete three consecutive weeks were excluded from the analysis.
The patient's general condition was poor and he showed a lack of appetite with consecutive weight loss.
Selection bias was explored by comparing baseline characteristics, overall survival, duration of follow-up, and complication and secondary intervention rates in patients included or excluded from the present study; in this analysis the latter patients were those who survived the first 6 months, and were excluded only owing to lack of two consecutive imaging examinations.
The lack of a single question on climate change after four consecutive presidential debates is a painful reminder of how little political power climate hawks have really built.
The main limitation of our study is the lack of surveillance in consecutive years, which could have biased results in case of an outbreak of one specific virus in a given year.
Finally, the lack of systematic and consecutive PCT assays in the population studied may have biased our results.
The lack of a menu?
The lack of a culture of reading?
Just lack of a jackhammer, you know.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com