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People who lack growth hormone -- for example, patients with a genetic defect or a tumor of the pituitary gland that prevents the hormone from being made -- have all these signs and symptoms of aging, and they are reversed when they take growth hormone injections.
Dr. Rimoin's studies also pinpointed genetic defects that caused particular skeletal or growth disorders — revealing, for instance, that pygmies are short not because they lack growth hormone but because they carry an inherited trait that makes them biochemically resistant to the hormone's effects.
Cawley doesn't entirely lack growth opportunities.
Long-lived Ames dwarf mice lack growth hormone, prolactin, and thyroid stimulating hormone.
These lack growth plates but the unaffected side of the spine continues to grow leading to spinal deformities [20].
Prosthetic and bioprosthetic materials currently in use lack growth potential and therefore must be repeatedly replaced in pediatric patients as they grow.
Similar(47)
We showed that, even though several mutant forms lack growth-suppressive activity, they preserve some functional activities of BAP1 in vitro.
He observed that the effects of aging also appeared in young people who lacked growth hormone for medical reasons.
The tiny creatures lacked growth hormone and insulin-like growth factor-1 (IGF-1).
One was the Snell dwarf, first identified in 1929, which lacks growth hormone and thyroid-stimulating hormone (TSH).
To investigate whether Lifeact-mEGFP was altering actin dynamics, we collected high resolution z-stack images of pollen that exhibited cytoplasmic streaming but lacked growth.
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