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One particular antidepressant was known by everyone to lack efficacy, yet the studies appeared to show that it worked as well as all the rest.
Alternative interventions to continuous positive airway pressure (CPAP) lack efficacy and safety or are highly complex.
Unfortunately, available therapies lack efficacy in preventing progression to its end stage phase.
In addition, certain agents routinely available for nonsquamous cell histologic subtypes, such as bevacizumab and pemetrexed, are contraindicated or lack efficacy in sqCLC.
Indeed, the co-discover of Lyme disease, Prof Allen Steere, has been stalked, threatened and abused for refusing to substantiate self-diagnosed CLD, in addition to his refusal to endorse long-term antibiotic therapy - a treatment course shown to lack efficacy.
The "accrual of high-level evidence," according to a review of studies published last year in an American Medical Association journal, shows "that the supplements lack efficacy across a range of health outcomes".
Similar(29)
As monotherapy, however, anti-angiogenic treatment lacked efficacy in randomized clinical studies so far.
Both infliximab and adalimumab have been shown to be effective in Crohn's disease while etanercept lacks efficacy in this disease.
Conclusion: Under the conditions of this trial, chlorhexidine vaginal irrigation lacked efficacy in the prevention of clinically diagnosed maternal and neonatal infectious morbidity.
GRK2 lacked efficacy at both endothelin and alpha(1 -adrenergic receptors despite massive overexpression.
Therefore, we cannot exclude that sepsis further aggravated PPAR-β/δ down-regulation and thus contributed to the lacking efficacy of GW0742.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com