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Further, data may lack comparability, especially because mesothelioma is rare and difficult to diagnose.
Studies in the same disease or treatment domain might lack comparability if they are based on different vignettes.
These analyses indicate that our ability to conduct weight-of-evidence assessments of the epidemiologic literature on neurotoxicants may be limited, even in the presence of multiple studies, if the available study methods, data analysis, and reporting lack comparability.
A concern with this approach is that population controls sampled from a convenient population register may not be representative of the true population at risk of being a member of a hospital case series; population controls may also lack comparability in recruitment fraction and recall of information [ 1- 5].
We did not formally address methodological quality or adherence to established guidelines, and there may be good reasons for different study designs for different purposes that lack comparability but are all, each by themselves, legitimate and in concordance with best practice recommendations.
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As with RCTs, quasi-experimental studies lacked comparability.
These parameters were either not measured or lacked comparability between the two surveys.
Finally, this study has the limitations associated with a descriptive approach and lacks comparability in many respects.
The scale of the quality aspect 'information after discharge' was adjusted in 2007 and therefore lacks comparability between the years 2006 and later years.
In epidemiology, typical examples of bias are the lack of comparability of study groups (e.g., cases and controls selected from two different populations), lack of comparability of exposure or outcome information (e.g., cases prone to overreporting past exposure as compared with controls), and selective publication of studies showing an effect (or the lack of an effect).
Without revealing the two logics of policy intervention, there results a lack of comparability of research findings, and this hinders a thorough empirical comparison of both approaches.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com