A special case was paradoxical sleep, an epoch known to lack autonomic function control (open-loop), in which a great majority of the recorded units (83%) exhibited theta phase-locking.
Although the ovary is densely innervated, with autonomic nerves associated with thecal vessels of all follicles regardless of the stage of development, the luteal vessels lack autonomic innervation [ 108].
The high ratio of pericytes to ECs in the retina and brain may be of particular importance in regulating local blood flow because the microvasculature of the CNS lacks autonomic innervation and precapillary sphincters, which contribute to autoregulation in other microvascular beds [33].
Our study is however limited in the extent to which we can ascribe poor performance on the IGT to such lack of autonomic emotional inputs because we did not obtain concurrent measures of autonomic arousal.
Although electronic pacemakers are an excellent therapy, their persistent shortcomings (need for monitoring and replacement, indwelling catheter electrodes in the heart, possibility of infection, lack of autonomic responsiveness, geometric limitations with respect to pediatric patients) are sufficient to warrant a search for better alternatives.
This lack of autonomic balance is known to be linked to multiple disease states, including cardiovascular disease[47].
Also, the headache attacks in this patient have a seasonal periodicity but lack cranial autonomic symptoms (CAS) such as lacrimation or rhinorrhea.
Beyond the standard clinical characteristics, features like side shifts (12.6 %), location of maximal pain intensity outside the first trigeminal branch division (10.2 %), lack of autonomic features (7 %), presence of associated features of migraine and aggravation by physical activity (10 %) were encountered.
It is possible that temporary targeting of CD14 MDC, e.g. by CD14 antibody [ 109], small interfering (si RNA [ 116], or other approaches targeting tissue macrophages, may result in the regression of unstable (lack of autonomic innervation) "tissue control units" in malignant tissues, leading to activation of NK cells, and subsequent regression of malignant stroma and elimination of tumor cells.
In ICHD-3 beta, this criterion was revised to a lack of "cranial autonomic symptoms" [12].
Those included side shifts, maximal pain intensity outside the first division of the trigeminal nerve, lack of all autonomic features or lack of a sense of restlessness or agitation, as other studies have also shown [5, 7, 16, 33].
