The resultant approach not only shows a significant reduction in the computational time while maintaining model accuracy, but also provides an automatic method for modifying the fracture related parameters - a laborious process in the traditional workflow.
QSAR modeling workflow completely automates the laborious and iterative process of modeling to tackle different problems.
In contrast, the front end code and assets that Supernova generates is designed to be handed off to a developer to write the required logic and 'wire up' the app to backend code and databases, but with one repetitive and laborious step less than the current designer/developer workflow.
Many modern business environments employ software to automate the delivery of workflows; whereas, workflow design and generation remains a laborious technical task for domain specialists.
For workflows such as this, which may be laborious and time consuming to perform manually, software that could orchestrate the operations and transfer results between computers in a seamless and automated fashion would offer major efficiency gains.
However, the requirement for isotope-labelled standards makes proteomic workflows expensive and reduces flexibility, as their production is laborious and applicable only to samples for which these standards can be obtained or generated (please see Discussion).
This could make it more difficult for curated databases to leverage 'general purpose' tools and could ultimately slow progress by making it more laborious to incorporate new tools or to upgrade the pipeline supporting the curation workflow.
INPP5F may be a novel, easily assessable biomarker in CLL, because its prognostic significance of INPP5F expression remained detectable in the set of unselected PBMCs, and this may support the clinical feasibility of this biomarker as the analytical workflow may not require separation of B cells as for ZAP70 or laborious assessment of the IGVH mutational status.
However, PCR amplification is too laborious for large-scale NGS downstream applications and risks being a bottleneck in the sample preparation workflow; consequently, more appropriate PCR procedures were developed.
In order to lead to a higher sensitivity and to considerably faster results, the laborious procedure presented in the manual of the manufacturer was completely modified by us resulting in a workflow which was very similar to that of the former AMS ELISA.
Workflow is pretty handy.
