For it to become substantially more than that – let's say reach 10percentt as discussed earlier – people not only need to believe they can make an attractive return but also that it's not that hard or laborious to do.
Ducts can be seen entering, branching within and leaving a thick section, so it is possible to follow the ramifications of all ducts throughout a whole breast, but very laborious to do so by manual methods.
Although one could determine if any of the relatively small set of index SNPs for a particular disease is located within a mapped regulatory element by simply visualizing the location of the SNP and the location of functional elements on a genome browser, it would be quite laborious to do this for the many hundreds of the SNPs in high LD with the index SNPs.
While we have done this in the past (Southworth, 2008), in practice, this is a somewhat painful and laborious procedure to do rigorously and instead here we chose to quantify the %closed state by SAXS.
Link reveals the dreary underside of the domestic fantasy; running a self-sustaining farm, even a small one, is costly, unpredictable, back-breakingly laborious — and nearly impossible to do alone.
That said, we still need to do the laborious work of identifying the right stocks to buy.
It began as Rosetta@home, a project using down-time of computers throughout the world to do the laborious calculations needed to determine the shapes of proteins, strings of amino acid crucial to the cells of every living thing.
But before any of that, somebody had to do hours of laborious, exacting work preparing articles about, and excerpts from, the papers for publication.
Still, he's the one having to do most of the laborious exposition here, while all the fun is in the barmy delusions of Florinda Bolkan.
As you read this, we'll be agonising over our decision - laborious work, just like floor-scrubbing, but someone has to do it.
"There's a lot to keep track of," said Mr. Hill, "and if we had to do it with spreadsheets it would be laborious".
