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There is no obvious way to control for this, barring laborious cross-fostering and embryo-transfer experiments.
Prior to Engelbart's inventions, laborious and error-prone keypunch cards or manually set electronic switches were necessary to control computers, and data had to be printed before it could be viewed.
This is typically an optimal control problem, which is often laborious to solve and can result in an input profile that is difficult to realize experimentally [ 18].
Books are small, easy to conceal and laborious to tag.
But this is pretty laborious to do it gene by gene and then assemble them.
Nevertheless, a limitation is the survey questionnaire of ANP too laborious to fill out [80,81].
It is thus laborious to distinguish these two species, even by molecular methods [7, 39].
Data- bases are notoriously complex and laborious to install; once in, they are painful to extract.
Using forests for building materials is way too laborious to survive in the 21st century.
Personal Medical Services (PMS) and Alternative Provider Medical Service APMSS) contracts are more flexible [ 22] if more laborious to manage.
Eflornithine is expensive, is laborious to administer, and lacks efficacy against T. b. rhodesiense.
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