These protocols required laborious processes for purification and refolding.
For fans accustomed to the laborious process of scouring for concert listings on blogs, MySpace pages, bands' Web sites, nightclubs' sites and e-mail, Songkick's personalized system can simplify the hunt and turn up news they might have missed.
Even if it's helping to speed up the laborious process of applying for a mortgage, consumers are unlikely to know that the magic being done on the back end is powered by Blend.
If it falls below that figure, it has to go through the laborious process of collecting signatures for every election, a daunting challenge for a Liberal Party with little money and fewer than 100,000 registered voters statewide.
Mr. Judt, who has two teenage children and is married to the dance critic Jennifer Homans, has a nurse to help him through the laborious process of getting ready for and into bed.
Fortunately, a few dedicated teams around the world work in concert to track down worthy and endangered films and begin the expensive and laborious process of reclaiming them for posterity.
He's a darling of in-the-know restaurant enthusiasts, his stature reflected in the decision of one prominent blog, New York magazine's Grub Street, to have him chronicle the laborious process of opening a restaurant for nine months before Tailor's debut in September.
This means that we need a laborious process of trial and error for setting the state number to obtain a good segmentation; it is infeasible for genome analysis to select an appropriate state number in each gene.
The laborious process of hand-molding, which had been used for 3,000 years, was superseded by "pressed" bricks.
