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The proposed approach requires only accurately measured product temperature profiles, easily obtained in a laboratory dryer.
Laboratory dryer was designed in such a way that drying could be done either with infrared energy or by convection.
A laboratory dryer and its data acquisition system were designed and constructed to enable a wide range of operating velocities and temperatures.
The only scale-up adjustment for center vials is for the contribution of radiation from the shelf upon which the vial sits by replacing the emissivity of the laboratory dryer shelf with the emissivity of the production dryer shelf.
The purpose of this study was to determine the dry layer mass transfer resistance, using a simple and rapid method, for various pharmaceutical formulations during primary drying in a laboratory dryer, using monitored product temperature profiles.
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The hot air convective drying characteristics of thin layer apple pomace were evaluated in a laboratory scale dryer.
Solutions of bendroflumethiazide in ethanol/water, ethanol/water/ammonium carbonate or methanol/water/ammonium carbonate were spray dried using a laboratory spray dryer.
In this contribution coupled DEM CFD simulations of convective drying of wood chips in a baffled laboratory rotary dryer are presented.
The Tc as measured by OCT FDM was found to be predictive of freeze-drying with a batch of vials in a conventional laboratory freeze dryer.
A minimum ice sublimation area of about 300 cm2 for the laboratory freeze dryer, with a chamber volume 107.5 L, was found consistent with data obtained during previous experiments with a smaller freeze dryer (52 L).
The present study investigated the effect of operating parameters of a laboratory spray dryer on powder characteristics, in order to optimise the production of trehalose and raffinose powders, intended to be used as carriers of biomolecules for inhalation.
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