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The majority of the frequently used approaches are time consuming and expensive and require skillful labor techniques, such as the high performance liquid chromatography [ 5], colorimetry [ 6], laser spectroscopy [ 7], fluorometry [ 8], ion chromatography [ 9], and enzymatic method [ 10].
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They chose labor intensive techniques, crossed the steep Andes to find feathers and plant fibers and designed patterns with hidden and symbolic meanings.
Unraveling the design principles that govern this spatial division of labor requires techniques to quantify the entire transcriptomes of cells while accounting for their spatial coordinates.
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Additional (but far more costly and labor intensive) techniques, such as titration with known amounts of stable isotope labeled 'proteotypic' peptides uniquely representing each proteins will be needed to obtain precise quantifications (reviewed in [20]).
Though this was achieved by the isolation of peripheral blood mononuclear cells immediately after specimen collection, the labor intensive techniques involved in this process and the need for technical experts in the field at the time of sample collection hinder its applicability in large scale multi center clinical trials.
Previously, characterization of genetic deficiencies has been performed by fairly low resolution or labor intensive techniques such as genetic linkage mapping, PCR analysis [ 7] and, more recently, by the application of snip-SNP [ 9, 10] and as a consequence many available deficiency strains remain poorly characterized.
But there are less labor-intensive techniques that can still make a big difference.
"Very few clay artists have the dedication to apply themselves to these labor-intensive techniques," Ms. Russell said.
They feature brilliant colors, enamel-hard surfaces, labor-intensive techniques and flat, geometric suggestions of landscape and architecture.
Considering the savings of time and labor, the technique is worth to be recommended.
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CEO of Professional Science Editing for Scientists @ prosciediting.com