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However, even in reports of successful DK [ 14- 17], the depth of sequencing was less than 0.3 (when the theoretical number of unique virtual tags was defined as 1.0), partly due to practical limitations, such as the low through-put rate and labor intensive methods required when using standard sequencers [ 33].
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Although the addition of isotopically-labeled internal standards to compensate for matrix effects are often considered a lengthy and labor intensive method [28, 56].
Identification of bacteria as performed in this work is a costly and labor intensive method that is not applicable in routine analyses.
Although the OPKA has been known as a labor intensive method, OPKA methods have been evolving rapidly and is now capable of evaluating multiple serotypes for many samples with only small amounts of sera [ 16, 28- 31].
Combination of CT scan with angiography has been found to increase the diagnostic specificity in some patients with pulmonary mold infections [ 24, 25]; however, this more labor intensive method has not yet become widely applied and is therefore not included into current clinical practice guidelines.
The impression of material density comes from his labor-intensive methods.
Installation art proved long ago that lots of space combined with lots and lots of one material, arranged by stupefyingly simple labor-intensive methods, can work wonders.
Arguing that the search for sustainability may make costly, labor-intensive methods newly attractive, he also makes a case for the psychological benefits of working with one's hands.
Often, the mere process of cooking with these outdated and labor-intensive methods needs to be its own reward, so I wasn't expecting all that much.
But the Congressional study found that some agencies did not even have policies for sharing watch-list information with other agencies, and that those that did often required complex, labor-intensive methods to cull information.
Mr. Calderon gave up truck driving in Arizona to use pesticide-free, labor-intensive methods to farm The Patch, planting cover crops and nitrogen-rich beans in the off-season to replenish the soil.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com