Sentence examples for labelling methodology from inspiring English sources

Thus, there was a difference in the labelling methodology for different subsets of the local data, with algorithm training relying on data with a reference diagnosis based on visual assessment only, and reporting performance measured with data that had reference diagnosis based on clinical follow-up.

An indirect labelling methodology was employed in preparing the microarray targets.

At least 95 of the 145 miRNA sequences detected by either labelling methodology, using our array, were predicted to be expressed in mouse tissues [ 37].

Using 100 ng of LMW RNA as starting material a strong fluorescent signal was detected, with some spots close to saturation, and we went on to use this labelling methodology to test a range of concentrations of miRNA starting material to determine the sensitivity threshold, and the dynamic range, for detection of our microarray, after target amplification.

Our objectives for this investigation were; to determine whether the sensitivity of detection of miRNAs can be increased by amplification as compared to a direct labelling methodology, and to determine whether an accurate representation of the original miRNA population is retained following amplification.

The diversity of the labelling methodologies that used to introduce the radioactive iodine into the target molecule are wide enough to make the selection of a specific route is of great interest.

The primary aim of this investigation was to examine target labelling methodologies that could be used for our custom miRNA microarray that did not require labour intensive steps such as gel purification, were sensitive and specific, useable at high-throughput and more affordable than multiplex RT-PCR assay.

Conclusion: A new labeling methodology was developed and successfully applied to the synthesis of clinically interesting radiotracers.

The straightforward labeling methodology allows for the placement of the fluorophore and quencher moieties at specific positions suited to studying the conformational change of interest.

Since in most cases the design and development of PET biomarkers is based on approved or potential drugs, there is a growing need for a general labeling methodology of urea-containing pharmacophores.

The objective of this study was to make nano-salbutamol sulphate (SBS) DPI, radiolabel it with Tc-99m using a novel surface labeling methodology, characterize the formulation and assess its in vitro and in vivo deposition in healthy human volunteers to estimate its bioavailability in the target area.