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It is possible to increase the selectivity of this technique by adding a label specific to the MP of interest.
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Users can label specific citations according to relevance to the original search.
Subsequent advancements in this field made it possible to use these contrast agents to label specific cell types and thus to monitor cells at the molecular level.
Similar to sMRI, fMRI can be used to label specific molecules with contrast agents [43], i.e., molecular fMRI [44].
We can also use quantum dots to label specific proteins within cells – great for medical research – and maybe even to make solar panels more efficient.
The only method to label specific endogenous DNA sequences is fluorescence in situ hybridization (FISH) which requires access to the target DNA and DNA denaturation, both conflicting with preservation of nuclear morphology.
Eric Ahren, a researcher at Carnegie Mellon, is working on a way to challenge some of those limitations by using fluorescent nanoparticles to label specific groups of cells, which can then be pinpointed with an incredible level of precision.
A paper published by Andrej Karpathy and Li Fei-Fei at Stanford University describes a computer-vision system that is able to label specific parts of a given picture.
The application, called TAL effector-mediated genome visualization (TGV), allows us to label specific repetitive sequences and trace nuclear remodeling in living cells.
FISH used with specific markers can be used to label specific chromosomes and target given genomes or particular regions on chromosomes (Cheng et al. 2007; Jiang and Gill 2006; Kopecky et al. 2008; Pinkel et al. 1986).
This cell type was non-migratory and expressed the radial glial marker 3CB2 (Fig. 1B), which was recently shown to label specific isoforms of the intermediate filament protein vimentin [26].
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