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Both studies were single-arm, open label phase II studies.
Patients were seen and assessed weekly during the open label phase of the trial.
The study incorporated a single-stage, open label, phase II design.
The study was an open label phase I pilot study with biomarker endpoints.
In the open label phase of the study, all patients received active treatment with adalimumab.
This study is a multicenter, randomized, active controlled, open label phase II clinical trial.
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GRACE was a multicenter, open-label, phase 3b study.
Bar-Or, A. et al. Rituximab in relapsing-remitting multiple sclerosis: a 72-week, open-label, phase I trial.
Fiedler, W. et al. An open-label, Phase I study of cediranib (RECENTIN) in patients with acute myeloid leukemia.
This was a single-institution, nonrandomized, open-label, phase I clinical trial with a standard 3+3 dose escalation.
Methods We enrolled boys with cerebral adrenoleukodystrophy in a single-group, open-label, phase 2-3 sandty and efficacy study.
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