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As a result of this procedure, each target was given a label of "normal", "deletion" or "amplification" as previously described [ 2, 3, 13].
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The French Inserm experts write: "The group of experts recommends using health visits with their systematic pediatric monitoring from young childhood through adolescence to improve the efficiency of screening of both conduct disorder and its risk factors and simultaneously correct any previous incorrect labeling of normal behavior as pathological.
The Atg16L1-immunogold labeling of normal cells revealed concentrations of staining that appear to label "clusters" of smaller vesicles.
Labelling of normal appearing axons by NPTX2 was widespread in both PD (Fig. 3) and control brains.
Double labeling of normal rat kidney sections with PDK1 and Wilms tumor 1 (WT1) antibodies confirmed that PDK1 is expressed in the nuclei of podocytes.
In our previous work, we showed that labeling of normal IMR-90 human fibroblasts with I-IUdR triggers changes in gene expression of about ten times fewer genes as gamma-radiation exposures delivered in bioequivalent doses [ 7].
A statistically significant difference (P=0.001) was observed between the mitotic index and Ki-67-labelling index of normal spermatogonia and those of the CIS cells (Table 2).
Terminal deoxynucleotidyl transferase-mediated dUTP nick-end labelling staining of normal oral mucosa revealed rare apoptotic cells within the epithelium and also within the connective tissue, the latter appearing to be apoptotic lymphocytes.
PHQ9 is a screening not diagnostic tool constructed using a definition of depression (Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition and International Classification of Diseases 10th Revision); it has been critiqued as being over simplistic and risks labelling components of normal human experience as a disorder.
Slower cell cycle kinetics and the ability to retain DNA label are characteristics of normal tissue stem cells that have been assayed by [H]deoxythymidine or BrdU incorporation [ 29, 30].
For each hybridization, we labelled 5 μg of normal (Cy3) and 5 μg of tumour (Cy5) mRNA.
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