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In the present study we focused on c2 sites and LA genes but roles of c1 sites in the control of non-LA genes are less clear at present and should be addressed in future studies.
Thus, c2 sites are likely to be essential for the regulated expression of LA genes.
The category of genes with all these characters will be referred to as "LA genes" hereafter.
When classified toposite densities in the genic region were compared, c1 sites were significantly enriched in non-LA genes, whereas c2 sites were concentrated in LA genes (Figure 5C).
Re-analysis of their data indeed showed a high incidence of LA genes in the monoallelic expression group (Figure S11).
This type of interaction may repress the transcription of LA genes by condensing the chromatin structure of promoter region.
Similar(46)
"La, la, la, la.
The la gene was located between R728 and C459B, of which the positions were 63.8 and 65.2, respectively, in the map by Harushima et al. (1998).
A large proportion of LA gene (81%) contained toposites as compared to non-LA genes (40%).
The proportion of LA gene in total A1 genes was significantly higher than that of other gene groups (Figure 2D).
A higher proportion of A1 genes (68%) shared statistically significant GO terms with LA gene as compared to other gene groups (see also Figure S6).
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