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When examining the corresponding tertiary structure information, we observe that the loops of the hairpins P17 and P17.1 are engaged in pseudoknots with loops L (named P6).
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However, d-NAME, an isomer of l-NAME, can scavenge hydroxyl radicals at equal rates to l-NAME.
L-arginine, an antagonist of L-NAME, reverses the effects of L-NAME.
l-Arginine restored acetylcholine-induced dilation after l-NAME treatment.
L-NAME alone caused no significant change in body temperature.
or l-NAME (100 mg/kg i.p). in control rats.
Successful mating rates were as follows: 90% (9/10) in control females with control males, 67% (8/12) in control females with L-NAME males, 47% (7/15) in L-NAME females with control males, and 31% (4/13) in L-NAME females with L-NAME males, P =.007 (control versus L-NAME females).
Both Ppa and Psa were decreased more with SNP in the L-NAME than in the no L-NAME group.
The l-NAME-inhibited relaxation was restored by treatment with l-arginine (5×10−4 M).
l-arginine and l-NAME by themselves did not induce conditioned place preference.
The response to l-arginine was blocked by l-NAME preadministration.
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