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The glucose tolerance status of these participants were characterised according to WHO criteria [1]; normal glucose tolerance (n = 4,568), impaired fasting glycaemia (n = 508), impaired glucose tolerance (n = 707), or screen-detected T2D (n = 256); 125 had known treated type 2 diabetes and were excluded from the quantitative trait analyses.
Therefore, adjustments were made to account for the substantial underreporting of known treated cases.
We cannot exclude that individuals with prior CVD and/or known (treated) hypertension have received dietary advice to reduce their salt intake, which may have masked the associations.
According to protocol, patients with diabetes were identified as those with known (treated or not) type 2 diabetes prior to admission or with type 2 diabetes diagnosed during hospitalization (except transient glucose intolerance in relation to ACS).
For this analysis, we selected from the IeDEA database all HIV-1 infected naïve adults (16 years or older) with gender and date of ART initiation known, treated with a first line ARV combination including two nucleoside analogues (NRTIs) and one protease inhibitor (PI) or one NNRTI.
All regression analyses were conducted in the whole study population and also in the subgroup of individuals without prevalent CVD and/or antihypertensive medication, because individuals with prior CVD and/or known (treated) hypertension may have received dietary advice to reduce their salt intake, which may mask any associations.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com