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Certainly, the cyclooxygenase enzymes are known targets of NSAIDs.
The same system could discover unknown associates of known targets.
I think about people who, even though they were known targets, had no protection.
"Search theory" and other approaches that focus on finding known targets efficiently are of little help.
This list includes many known driver genes (e.g., MITF), which CONEXIC correctly identified and paired with their known targets.
The penicillin-binding proteins (PBPs) are well known targets for the β-lactam antibiotics.
The error in degrees between actual and known targets was determined using video analysis software.
He discussed his comic strip, its critics and some of its best known targets, from Sinatra to the Presidents Bush.
All known targets have been alerted.
Another compound has three known targets.
More convincing validation would be to use compounds that have many known targets, such as vitamin E with 14 known targets and 4H-tamoxifen with ten known targets which were used in the test for TarFisDock (Li et al. 2006).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com