Follicular cells are known to progressively (trans)differentiate in culture, by upregulating markers of Sertoli cells or by luteinizing (Nekola and Nalbandov, 1971).
Calcineurin phosphatase inhibitors remain the mainstay of many antirejection regimens, and the agents are well known to progressively impair renal function.
First, there was an almost linear increase in age across categories of patients, and aging is known to progressively restrict bone marrow reserve and reduce circulating progenitor cell levels (6, 18).
Regular treatment with ICS is known to progressively reduce the patient's sensitivity to this stimuli (20), and we found that SCIT fully replaced this effect over 3 years.
The percentage loss of lower fornix for both methods of measurement (subjective and objective) was calculated using the equation: A correction factor for age was implemented, as the lower forniceal depth is known to progressively shorten with age.
Although the T- and B-lymphocyte compartments of the adaptive immune system are known to progressively deteriorate with advancing age (Geiger & Rudolph, 2009; Palmer, 2013), the impact of aging on the innate immune system remains unclear.
His solo career took off with singles like "Don't Be Cruel," but he became progressively known more for his drug and alcohol arrests.
Arvind Subramanian of the Peterson Institute for International Economics calls the rise of ever larger RTAs an "existential threat" and gives warning that "multilateral trade as we have known it will progressively become history".The debate about whether RTAs help or hurt the multilateral trading system has gone on for decades.
Again, though this law is progressively known, it is never known completely, and so the natural law is never exhausted in any particular articulation of it.
We confirmed the more differentiated phenotype of N-RAS mutant AML using RQ-PCR for the SIAT10 gene, which is known to be progressively up-regulated during myeloid differentiation (Figure 5E) [35E.
