Sentence examples for known modifiers from inspiring English sources

Mcl-1 and Bcl-2 are known modifiers of drug sensitivity.

These factors were included because they are known modifiers of health care utilization (21, 22).

Expression of extracellular matrix molecules in control and diabetic rats CTGF and CYR61 are known modifiers of the extracellular matrix.

Additional file 1: Effect of known modifiers of p53 using the primary screening conditions with cDNA pools.

When adjusted for known modifiers of ALI expression, delayed treatment of shock and infection were associated with development of ALI.

In addition, they are known modifiers of the mechanical resilience of corneocytes and of the proteolytic desquamation of corneocytes, providing a likely explanation for the primary defect in Nrf2 transgenic mice.

Since age is a known modifier of ALS survival, [29] it was critical to determine whether the observed correlation was related to age and not to the disease process.

Indeed, recent work suggested that lunatic fringe (Lfng), a known modifier of Notch, promotes the lateral inhibition of neurogenesis, that Lfng loss of function by morpholino knockdown leads to increased expression of proneural genes and increased neurogenesis, and that transgenic overexpression of Lfng decreases neurogenesis [50].

For example, SPP1 is a known modifier of disease severity in Duchenne muscular dystrophy [ 18].

In addition, p62 interacts with and regulates the deacetylase activity of HDAC6, a known modifier of F-actin network involved in selective autophagy [ 74].

This is quite a relevant finding as alcohol intake is a well known modifier of disease progression in chronic hepatitis C [ 12].