However, phenotype similarity information was not taken into consideration, and newly detectable associations were limited to diseases with known associated miRNAs.
The method also identifies associations between highly localized diseases and known associated cell types, including lens epithelial cells and retinal diseases (q=0.005).
Based on this definition of the association, the set of collected human protein complexes and the set of known disease phenotype-gene associations, we constructed 282 disease phenotypes and their known associated protein complexes (See in Additional file 1: Table S2).
The 75 known associated markers were defined by including, for each MS-associated marker listed in the National Human Genome Research Institute NHGRI GWASAS catalog (http://genome.gov/gwastudies/), a single best tag at r > 0.4 from the set of 360,557 markers if available.
In contrast to the known associated HLA alleles in Caucasians, we found a whole distinct spectrum of associated alleles.
They behave as parasitic elements and usually have no known associated function that is advantageous to the host.
In addition to the maleic acid with less known associated diseases, a withdrawal drug sibutramine was used to evaluate the ability of ChemDIS to identify known associated diseases.
Chronic cough may persist despite systematic evaluation and medical treatment of known associated diseases such as asthma, rhinitis, and gastro-esophageal reflux.
For patients with severe uveitis-related complications or a known associated inflammatory disease such as juvenile idiopathic arthritis or Behcet's, the nature of the results may have been different.
Computation of the WID, via a well-known hash function h (e.g., SHA-1 used for 802.11i [22]), is done as follows: WID = A predetermined WID, ESSID not known, WID = h ( AP ′ s ESSID ), ESSID known but not associated, WID = h ( AP ′ s ESSID | | AP ′ s BSSID ), ESSID known & associated, (2).
Moyamoya syndromes (MMS) correspond to moyamoya angiopathy associated with other neurological or extra-neurological manifestations, with or without a well-known associated inherited or acquired condition.
