Sentence examples for knowledge we designed from inspiring English sources

Based on this knowledge we designed new analogues of GR 113808 by introducing two bioisosteric modifications: firstly, the indole ring was replaced by a naphthalene one and secondly, the ester linkage was replaced by an amide group.

To address these gaps in knowledge, we designed the current study to test the hypothesis that in critically ill patients with sepsis, the extent of glycocalyx disruption as measured by plasma syndecan-1 levels is associated with development of ARDS and that glycocalyx degradation is more extensive in non-pulmonary sepsis compared to pulmonary sepsis.

To our knowledge we designed the first individual-based dynamic framework to model pertussis transmission in the population.

In this study, combining pioneering work with our CD4 T cell epitope identification knowledge, we designed a protocol for functional peptide:MHC microarray production and a data analysis system suitable to evaluate the cytokine responses of primary human CD4 T cells.

Based on this knowledge, we designed the timing of post-challenge measurements in the present study.

With this knowledge, we designed a four marker multiplex PCR assay (QC2 assay), including the three primer pairs of the QC1 assay and primers for the KRAS fragment.

Taking advantage of the plant knowledge, we design a course angle controller to ensure closed-loop stability.

In addition to using this context knowledge, we design tensor data-structures, tensor algebra interfaces, and new tensor contraction algorithms and implementations to achieve 90+% of a theoretically derived peak on GPUs.

Utilizing global system knowledge, we design a modified game encouraging better operating points in terms of sum rate compared to those obtained using the iterative water-filling algorithm and show how such a game can be imitated in a decentralized noncooperative setting.

To address the imbalanced classification problem without using any priori knowledge, we design a novel method that reformulates the imbalanced classification problem as a partial ranking problem.

To address this knowledge gap, we designed equipment and protocols to measure the metabolic responses of a common coral reef fish (juvenile ambon damsel, Pomacentrus amboinensis) to chemosensory and visual stimuli of a common predator (adult yellow dottyback, Pseudochromis fuscus).