On the other hand, if you don't do it, it's simply lost". He says our knowledge and ability to recreate the works of great Western composers from Palestrina to Bach is based on written records "that have long slept in dusty attics". "The fact is that writing it down does change it, but it's already changed.
While it is to our knowledge not possible to recreate exactly the same methylation patterns in vitro as seen in the primary tissue, we could investigate here the functional consequence of global LY75 promoter methylation, suggesting a direct link between methylation and transcriptional activity.
Good study documentation will allow for an individual with basic knowledge of the particular project to recreate the events of the study.
It is all too often the case that there is insufficient context to recreate what was once institutional knowledge: the science is now effectively lost.
Back in the old days hardware manufacturers felt safe in the knowledge that no mere hardware hacker could attempt to recreate their inventions.
That's one of the only pieces of evidence that we have pointing to them, but it would take very, very insider knowledge of this old implant to be able to recreate this overlap," Huss added.
Whilst it would be possible to reconstruct a Fortran implementation from extant documentation, such reconstruction is unlikely to recreate an unbiased implementation given prior knowledge that the reconstruction would be used test for inadequate assumptions.
It seeks to recreate the links between this long search for knowledge and today's science and comprehension by paying tribute to the visionary scholars whose goal was to model – in spheres, circles and ellipses – our fascinating cosmos.
The simulation enabled us to test whether the information in the network reconstruction is sufficient to recreate the expected behaviour reflecting the existing biological knowledge about the system or not.
But the problem is more severe today, Mr. DeLong says, because the knowledge we are about to lose is more complex, abstract and costly to recreate.
