Our empirical determination of the importance of Cel61A illustrates that it can be difficult to predict which enzymes will be important, and at what proportions, based solely on our (imperfect) knowledge of the structures of plant cell walls and our (imperfect) knowledge of the full range of enzymatic activities of the large number of proteins secreted by lignocellulolytic microorganisms [ 3].
But above all else, we need to be honest with young people, not withhold from them knowledge of the full range of human sexuality that does exist in reality, which they will encounter and engage with in the world outside school and which they need to be prepared for.
There are databases of, and computer models to predict, aquatic narcosis and, in some cases, excess aquatic toxicity such as ECOSAR [1] but there remains a need for better sharing of human knowledge about the full range of environmental and human toxicological hazards.
The challenge for creative scientists is to direct knowledge across the full range of cultural development.
Our results show that testing of dead wild animals for EBOV should not be neglected and may improve our knowledge regarding the full range of dead end hosts.
Private patients select their preferred consultant, receive continuity of care and feel secure in the knowledge that the full range of emergency services within the public system is available if needed.
While it is anticipated that as use of such measures diversifies the evidence base will expand, there are some gaps in current knowledge about the full range of psychometric properties of many of the shortlisted measures.
Although malaria may be responsible for > 50% of febrile illness episodes in this holoendemic area, 29 knowledge of the full range of prevalent etiologies is important to improve the empiric treatment of this syndrome.
Although differences in sensory properties among sweetener types are known to involve formation of new compounds during thermal decomposition at elevated temperatures (e.g., Hutchinson et al. 1999), our knowledge of the full range of chemical interactions that occur during baking with high-potency sweeteners is still incomplete.
Previous studies were limited by relatively small case numbers, and because, until recently, food databases did not contain the comprehensive range of flavonoids present in the diet, no previous studies, to our knowledge, have examined the full range of flavonoid subclasses in relation to ovarian cancer risk.
