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Our data extend the current knowledge on the functions of LCAT, indicating that LCAT activity is an important modulator of processes associated with diet-induced hepatic lipid deposition.
Much of our knowledge on the functions of genes, both in health and disease, is derived from molecular biological experiments with specific model systems, which often provide a biased and context-specific view of gene functions.
However, the meaning of these changes often is not clear because of insufficient knowledge on the functions of specific oxylipins.
Current knowledge on the functions of irisin and the mechanisms involved in exerting its actions is exceptionally limited and only allows for hypotheses to be made.
The successful application of high-throughput sequencing technology to systemically identify plant miRNAs has greatly advanced our knowledge on the functions of miRNAs in plants in recent years.
In this review we summarize the current knowledge on the functions of exosomes in the diagnosis, tumorigenesis, metastasis, microenvironment, drug resistance and therapy of breast cancer.
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Here, we review and synthesize existing knowledge on the functioning of kelp species as biogenic habitat providers.
The research explosion that followed the discovery of TLRs more than a decade ago has boosted fundamental knowledge on the function of the immune system and the resistance against disease, providing a rational for clinical modulation of the immune response.
Current knowledge on the function of histone modification regulation and recognition suggests that there are both conservation and difference between plants and other eukaryotic systems in chromatin mechanism of gene regulation.
Knowledge on the functioning of the HPA axis under acute or chronic challenge is also a key to understanding the intimate link between stress response and the pathogenesis of depression [40].
Thus knowledge on the function of EpCAM in these cells is valuable and requires additional work.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com