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The best knowledge on metabolites can be found for pharmaceuticals.
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With the increasing applications of metabolomics technology on both microbial and clinical samples from patients with appropriate controls, we expect to witness an exponential expansion of our knowledge on microbial metabolites, including the discovery of novel metabolites and potential biomarkers for diagnosis of infections such as melioidosis.
With the increasing applications of metabolomics technology on both microbial and clinical samples from patients with appropriate controls, we expect to witness a gross expansion of our knowledge on microbial metabolites, including the discovery of novel metabolites and potential biomarkers for diagnosis of infections such as tuberculosis.
Knowledge on systemic metabolites associated with deteriorating glucose tolerance may elucidate the pathogenesis of diabetes and holds potential for prevention.
The applications of these polpores in traditional medicine, and knowledge on their metabolite profile have been extensively reviewed by Grienke et al. (2014).
We have extended the discussion about the following implications: that knowledge on ongoing metabolite exchange is essential for understanding the physiology of cells, as it shows that in a community, metabolic networks operate non-autonomously.
FBA does not require knowledge of metabolite concentrations or detailed information of enzyme kinetics.
The approaches mentioned above are complementary and enrich the knowledge on these secondary metabolites.
JH provided bioinformatics knowledge on the identification of metabolites.
The knowledge on the regulation of secondary metabolites (SMs) has traditionally been important for the design of culture media, for process control strategies, and reactor design.
Integrating food and nutritional metabolomic approaches can increase our knowledge on the bioactivity of food metabolites, and may increase evidence for metabolic mechanisms by which foods elicit important health effects (Capozzi and Bordoni, 2013; Herrero et al. 2012).
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