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Knowledge of these defects and the abnormal mechanisms by which they produce cancer provides a rational basis for drug design.
Several attempts were undertaken to use the knowledge of these defects to design new drugs, which might either activate or re‐activate the apoptotic machinery of tumor cells.
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Those with knowledge of the defects spoke on the condition of anonymity, as did others, because they were not authorized to discuss the matter.
To develop a firm understanding of the mechanical properties of any given material, it has been established that in addition to understanding the crystal structure, a knowledge of the defect structures and their properties is also essential [1,2].
These studies may, however, be biased by prior knowledge of reported defects in mitochondrial function.
Together, these findings highlight the importance for a detailed knowledge of genetic defects in tumors to identify those patients who will most likely respond to specific genotoxic drugs.
Familiarity with the basic components of the UPS and knowledge of UPS defects in neurological diseases will definitely be of future importance in neuropathology.
Indeed, emerging knowledge of gene defects in males (Klonisch et al. 2004) suggests a common cause for cryptorchidism and sensitization to a tumor-inducing agent.
Knowledge of Birth Defects among Ghanaian Pregnant Women attending Antenatal Clinics at Three Selected Hospitals Section A: socio-demographics Kindly provide the following informations: 1. Age (years) 2. Education level: a.
This improves our knowledge of the initial defects at a concrete interface.
The knowledge of possible coating defects is the second step required to successfully use a multilayer curtain coating line.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com