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The knowledge of the pathways enables those who develop the drugs to more tightly focus their thinking upon potential diagnostics and therapeutics.
This goal could not be achieved without knowledge of the pathways and rates of supply and consumption of all atmospheric constituents at all times.
Hence, it is challenging to identify these species without prior knowledge of the pathways of catabolism.
Designing vaccines that elicit effective CD8+ T cell responses requires a thorough knowledge of the pathways of antigen presentation in vivo.
Given the current incomplete knowledge of the pathways comprising of miRNAs and the down-stream target proteins in cancer, more studies are needed to be focused on these dys-regulated miRNAs.
Another approach to measuring pathway fluxes using quantitative isotope tracking, relies on detailed and accurate knowledge of the pathways present and active.
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The metabolic engineering approach is a promising tool to improve the key component which is limiting in many of the medicinal plants but, prior knowledge of the pathway leading to accumulation of the secondary metabolite is prerequisite before any molecular intervention.
Knowledge of the pathway can be characterized by six probabilities p(h1),.., p(h6) that are associated with these hypotheses.
This can be limited by a lack of preexisting knowledge of the pathway of interest.
However, knowledge of the pathway during mammalian heart development is limited.
These studies were hampered by a lack of knowledge of the pathway of entry of immune factors in the CNS.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com