Sentence examples for knowledge of substrates from inspiring English sources

Quantitative three-dimensional information about both bulk and surface structural features of substrates needs to be obtained to expand our knowledge of substrates.

Knowledge of substrates of the OSGP-containing STYKs and their sites of phosphorylation is required to understand their role in regulation of functions of glycoproteins.

Much work needs to be done on this area of protein kinases, and current knowledge of substrate-binding mechanisms is rudimentary.

Knowledge of substrate elasticity, for example stiffness, and optical measurement of substrate distortion can be combined to produce estimates of the traction forces of cells.

The knowledge of substrate specificity and toxicity patterns is needed in order to select strains with the required properties for efficient bioremediation.

Knowledge of these substrates and the generated fragments is crucial for a thorough understanding of the functional implications of caspase-mediated proteolysis.

Roughly one-quarter of these CYPs are classified as orphans with little or no knowledge of their substrates and physiological significance.

As knowledge of the substrates of cognition becomes more crystallized, this will guide the design of cognitive studies in PD and will shed light on appropriate therapeutic strategies given a wide range of symptoms and individual patient priorities.

Knowledge of its substrates is limited [2,15,16]: it catalyzes the N-oxygenation of short-chain aliphatic primary amines such as N-octylamine [12] and the S-oxygenation of S-methyl-esonarimod, an active metabolite of the anti-rheumatic esonarimod [15,17].

Using indirect calorimetry, only whole body net balances of substrate metabolism can be described without knowledge of localized substrate oxidation or biosynthesis rates.

Recent studies have combined these approaches with the examination of evolutionary conservation and interaction networks to better understand kinase-substrate relationships [12].While such approaches have expanded our knowledge of kinase-substrate relationships, it is clear that many remain unidentified or uncharacterized by current methods.