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Better knowledge of signaling pathways has enabled the development of new cancer immunotherapy.
Both models (1) and (2) are very much simplified relative to current knowledge of signaling pathways.
Using experimental manipulations rooted in knowledge of signaling pathways, scientists can decipher the role of phosphorylated intermediates in cellular responses provided they are quantifiable.
Knowledge of signaling partners for orphans and crosstalks is a crucial component in elucidating a cell's wiring diagram towards a system-level understanding of cellular signaling.
Of particular relevance is to gain new knowledge of signaling and metabolic pathways in muscle involved in myopathy and early molecular markers applicable in clinical setting.
If so, the full discovery and understanding of biological processes underlying CRC on a genomic scale would be possible only with a more stringent approach, which requires an extensive knowledge of signaling mechanisms in all biological processes considered.
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It has been noted that the knowledge of signalling transduction pathways in Plasmodium is fundamental to aid the design of new strategies against malaria.
The major problem of this uncertainty is the lack of knowledge on signaling pathways mediated by nutrients.
In many detection applications, the knowledge of signal and/or noise is limited, incomplete, or imprecise.
In [2], an optimal BPSK receiver is derived assuming Rayleigh fading and no receiver knowledge of signal parameters.
The authors show that their technique is quite robust and does not require the knowledge of signal or noise statistics.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com