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The specific objectives of the evaluation are set out in figure 3. It is intended that the evaluation will produce local knowledge of relevance to the participants and to the programme as well as generalisable knowledge of broader interest to those leading and evaluating integrated care initiatives.
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With this case study, we therefore wanted to explore whether, and to which extent, traditional and local ecological knowledge are of relevance for predicting and coping with harsh winter conditions in an area where physical and economic infrastructure is particularly weak.
Given inputs of just the score and the pixels on the screen, and control of the games buttons – again without any knowledge of their relevance – it was able to play as well as a human after a few hundred games.
We presently do not have precise knowledge of the relevance of each factor.
To perform the gesture without knowledge of its relevance to a learning objective is unlikely to benefit learning.
A better knowledge of the relevance of molecular mediators of migraine as well as their central and peripheral actions may provide clues to the development of future new drugs directed to different targets of the migraine pathophysiologic process.
Finally, it is tempting to define the effect sizes of cognitive domains and effect sizes of the association with patient characteristics in terms of small, moderate or even large effect sizes, but since the lack of knowledge of clinical relevance (instead of statistical significance) these magnitudes of numbers have to be interpreted with caution.
Another weakness of our study was our knowledge test which was constructed by medical doctors paying attention to factual knowledge of medical relevance.
This increased knowledge of the relevance of various mechanisms to drug resistance in vitro should help identify better strategies for possible circumvention of drug resistance in cancer patients.
The measures selected for this analysis were based on a priori knowledge of their relevance for their specific mediator groupings, but availability (and lack thereof) also influences which individual components can be included in the analysis.
It may be that conversations about CKD with stage 3a patients are framed as reassurance [ 19] and thus provide ambiguous understanding and inconsistent knowledge of the relevance of CKD to patients overall health.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com