Sentence examples for knowledge of receptor from inspiring English sources

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Designing of new molecules based on the knowledge of receptor and the available ligands is well-known as Structure Based Drug Design SBDDD).

Again, this model predates knowledge of receptor proteins.

Detailed knowledge of receptor driven tumor dissemination may also provide new ways to overcome drug resistance.

(5) Lastly, the comprehensive ABA allowed the present survey to fill in many gaps in our knowledge of receptor expression using ISH.

This also contributes to fixing the receptor binding affinities of rHuEPO and darbepoetin, whereas the knowledge of receptor binding affinities of these two ESAs is well documented in the literature.

Therefore, although knowledge of receptor distribution in cancer tissues is of utmost importance and has significant clinical implications, inconsistencies in the published literature regarding expression of individual receptor subtypes other than SSTR2 impede the development of novel targeted therapies.

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However, these studies do not rule out the possibility that dimer could bind and activate the receptor, and therefore knowledge of receptor-binding characteristics of the dimer is also essential.

Identification of candidate genes potentially involved in the regulation and structural organization of olfactory signaling pathways in fish should contribute to extend knowledge of receptors and auxiliary proteins underpinning olfaction.

This brief survey has touched upon the very first steps of HIV infection to illustrate how the pathogenesis, development of some types of anti-retroviral drugs and approaches to vaccine discovery have been aided by knowledge of receptors and entry processes.

Key to this approach will be knowledge of which receptor or combination of receptors mediate midkine function in the brain.

A better in-depth knowledge of peptidic receptor has permitted more extensive research and development of new radioligands.

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