Sentence examples for knowledge of molecular evolution from inspiring English sources

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In addition to contributing to our knowledge of molecular evolution, the presence of duplicated genes with shared function in the zebrafish genome provides the novel opportunity for fine-tuned analyses of gene regulation.

Understanding the basis of this finding may contribute to the better knowledge of molecular evolution of NCS proteins as well as of important fields as the origin and fate of duplicated genes and of functional innovation.

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Here we present the first, to our knowledge, extensive study of molecular evolution of fungal mating-type genes in relation to reproductive strategy.

Given the complex nature of interlocus gene conversion and crossover, we provide a framework to explore their interplay to help increase knowledge on molecular evolution within segmental duplications under more complex scenarios, such as demographic changes or natural selection.

Therefore, the accumulation of experimental data on the secondary structures and enzymatic features of RNase H from many studies of its biological significance has provided us with an opportunity to use this knowledge in the field of molecular evolution.

To select a partitioning scheme, phylogeneticists typically start by grouping together putatively similar sites in an alignment into homogenous data blocks, using a priori knowledge of the variation in patterns of molecular evolution among sites [ 7, 10].

For example, the McDonald-Kreitman test [10], which uses contrasts of polymorphic and fixed variants to test the neutral model of molecular evolution, requires no knowledge of protein structure or specific functions of residues or domains.

Many forms of genomic analysis rely on indirect inferences of molecular evolution based on modern observed sequences and would likely benefit from accurate knowledge of full evolutionary histories.

Integrating our knowledge of nucleotide substitutions with more detailed consideration of indel mutations is necessary to fully understand processes of molecular evolution.

The current analysis represents, to our knowledge, the first interactome-level evaluation of the relationship between the structure of the A. thaliana PIN and the patterns of molecular evolution of its components.

In the late 1960s, the geneticist Motoo Kimura proposed the neutral theory of molecular evolution.

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