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Further combining these significant pairs with prior knowledge of interacting TFs in ESCs led to five TF pairs: cMyc-E2F1, Nanog-Esrrb, Oct4-Zfx, Sox2-Oct4 and STAT3-Klf4.
Although 3C and its variants are excellent tools to study complex interactions, these methods require prior knowledge of interacting candidates, hence cannot be used for genome-wide profiling for all chromatin interactions.
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Since interactions of two proteins often result in one or more biological processes, it is important to gain knowledge on interacting partners of proteins and hence their functions.
"We believe we enjoy the best of both worlds with our offices for focusing and our hallway of knowledge for interacting".
Understanding cellular systems requires knowledge of the SCL of interacting proteins.
And we respect their knowledge and their experience in terms of interacting with them and motivating them to change their behavior.
Utopia Documents provides new ways of reading, of interacting with and ultimately of assimilating the knowledge embodied within research articles.
In conclusion, our assessment of interacting local and landscape effect adds to the current knowledge of seed predation and removal.
In this paper, we describe a complex Soar agent that uses and learns multiple types of knowledge while interacting with a human in a real-world domain.
This procedure can reveal interactions between the bacterium and the host without any prior knowledge of either interacting partner.
Further, knowledge of the interacting sites can aid in other domains of computational biology, including PPI network construction and simulated docking.
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