Sentence examples for knowledge of essentiality from inspiring English sources

However, a rational method for applying knowledge of essentiality from orthologues in other species is lacking.

Author's response: The aminoacyl-tRNA synthetases are a special case because the combination of their trees and knowledge of the essentiality of their function implies these are displacements.

Indeed, to our knowledge, the essentiality of DprE1 has not been experimentally investigated in any species of Mycobacterium or Corynebacterium.

Genome-scale metabolic models provide a valuable framework to interpret essentiality screens as they allow predictions of gene essentiality using current knowledge of the metabolic network whilst also providing an insight into incomplete or incorrect metabolic knowledge.

Using elaborated features characterizing network topology, sequence information and microarray data enables to predict essential genes from a bacterial reference organism to a related query organism without any knowledge about the essentiality of genes of the query organism.

Figure 6: In silico elucidation of the mechanisms of essentiality for the five genes selectively essential in ccRCC.

It was accompanied by a certificate of essentiality, issued by the Electricity Commissioners.

We also tested whether essentiality in multiple species improved the probability of essentiality.

To our knowledge, a systematic analysis with the aim of understanding the nature of a set of organisms in which presence of a gene is most predictive of essentiality has not been performed.

Protein size was predictive of essentiality in both organisms.

We then calculated the probability of essentiality of these genes.