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The present study proposes a method of gaining process knowledge and assisting in the robustness analysis and optimisation of a hydrophobic interaction chromatography step using a model-based approach.
This paper presents a methodology to gain process knowledge and assist in the robustness analysis of an ion-exchange step in a protein purification process using a model-based approach.
This paper describes a model-based approach that can be used to gain process knowledge and assist in the robustness analysis of an ion-exchange chromatography step using a model-based approach.
The society will use knowledge gained in the process in efforts to sustain threatened amphibians elsewhere.
It is shown that the knowledge gained in the process, e.g. the number of sampling points and the most appropriate training method, may be used to efficiently balance the required computational effort with the required level of accuracy.
The reason: corporations rarely invest in basic research, mostly due to the fact that they will be unable to reap the full financial rewards of the knowledge gained in the process.
This document highlights the continuum from development to commercialization and how knowledge gained throughout this process should be used to ensure that the product continues to have the desired CQAs.
As science progresses to unravel the mechanism of mammalian dosage compensation, it has become clear that with the in-depth knowledge gained of this process in the mouse, the challenge remains to extrapolate these findings to the human.
While this study is particularly relevant for the bio-pharmaceutical industry by prioritising a number of potential miRNA cell engineering candidates, the experimental design ensures that the data generated and knowledge gained on biological processes driving cellular growth are applicable to other mammalian systems.
The agent knowledge in the form of rule-based heuristics designed based on process knowledge gained through simulation under open-loop.
The project used the experience and knowledge gained by Tenaris Dalmine process and maintenance operators as foundation for initiating the conceptualization of a novel and approach.
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