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This process not only involves basic agreement on the variable definition, but it also requires extensive domain knowledge for interpreting terminology used by each data provider, particularly if information that would help with interpretation is missing.
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Unfortunately, these aspects of genetic architecture have not been addressed in most of the genetic association studies that provide the knowledge base for interpreting large-scale genetic association results.
Our study has illustrated a method for uncovering genomic interactions that is easily applied in an experimental setting, is comparative, and requires no a priori knowledge of interactions (although such knowledge is useful for interpreting the changes).
Laymen normally do not have the background knowledge for correctly interpreting such data and a misinterpretation could cause panic in the population.
She has moved from searching for mutations largely for the sake of knowledge to interpreting the genome to more directly help patients, which is, to her, the most exciting part of her research.
The lowest scores (<50 % correct) were for interpreting p values and for knowledge of viral influenza chemoprophylaxis.
A better understanding of how recombination affects genome evolution is crucial for interpreting genomic data; unfortunately, current knowledge mainly originates from a few model species.
In summary, a better knowledge of the natural history of this species is essential for interpreting its biology.
Knowledge of sex differences in typically developing adolescents can provide a basis for interpreting sexual dimorphisms in abilities and actions.
Good knowledge of the habitat requirements of the immature stages of mosquitoes is necessary for interpreting the effects of land cover.
Knowledge of protein-protein interaction (PPI) data quality and their limitations is critical for interpreting results and essential for using them as a reference set.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com