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Quantitative assessment of perturbation in global kinome may provide crucial knowledge for elucidating the mechanisms underlying the cytotoxic effects of environmental toxicants.
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Knowledge of their regulation is crucial for elucidating pathogenetic pathways and designing effective treatments for autoimmune diseases.
The first challenge for elucidating structures is to have a knowledge system of previously identified compounds, as well as mining tools for such data.
An overlooked prerequisite for elucidating food effects on drug PK is thorough knowledge of causative bioactive ingredients.
Our finding suggests that the utilization of external knowledge representing miRNA-mediated regulation of gene expression is substantially useful for elucidating the cancer phenotype.
Biofilter is a software tool that provides a flexible way to use the ever-expanding expert biological knowledge that exists to direct filtering, annotation, and complex predictive model development for elucidating the etiology of complex phenotypic outcomes.
This current data explain this perceived haploid phenotype and this knowledge can also be advantageous for choosing a knock-out target in a specific pathway or for elucidating target region for a knock in.
Consequently, knowledge of neutrophil functions is quite important, not only for understanding how the coagulation system is activated but also for elucidating the mechanisms involved in inflammation and host defense.
It was the year after James Watson and Francis Crick won the Nobel prize for elucidating the structure of DNA.
D.L. Purich and R.D. Allison, Isotope Exchange Methods for Elucidating Enzymic Catalysis.
Therefore, KpBest is a very powerful tool for elucidating the function and structure of hBest1.
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