We review here current knowledge about functions of AD susceptibility genes, highlighting cells of the myeloid lineage as drivers of at least part of the genetic component in late-onset AD.
As an essential step to gain knowledge about function of KLF6 in breast tumors, the expression pattern and sub-cellular distribution of KLF6 protein was analyzed in samples of human breast cancer along with the expression of ERBB2 as a tumor aggressiveness marker.
Although our knowledge about functions and regulation of mammalian LRP2s is extensive, insights into the properties of this receptor in other vertebrates may reveal important additional biological details.
Knowledge about functions can also inform future research seeking to develop new treatment approaches for NSI, and the possibility that treatment effectiveness may differ according to the functions present.
New knowledge about the functioning of the immune system and host pathogen interactions has stimulated the rational design of vaccines.
Within agent-based Ambient Intelligence applications agents react to humans based on information obtained by sensoring and their knowledge about human functioning.
Emergent information will improve our knowledge about the functioning of human-modified ecosystems in terms of plant-carnivore interactions [31] and, ultimately, about the services that carnivores provide as 'restorers' of fleshy-fruited plant assemblages within anthropogenic areas [25].
We still have only limited scientific knowledge about ecosystem functioning and particular taxa in this area.
A bigger network is synonymous with a better one when the knowledge about the functioning of the cell is available to accurately design the network.
Also, from clinical practice we know that (special aid) teachers lack knowledge about executive functioning and its relation to academic performance and behaviour in class.
