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As an essential step to gain knowledge about function of KLF6 in breast tumors, the expression pattern and sub-cellular distribution of KLF6 protein was analyzed in samples of human breast cancer along with the expression of ERBB2 as a tumor aggressiveness marker.
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We review here current knowledge about functions of AD susceptibility genes, highlighting cells of the myeloid lineage as drivers of at least part of the genetic component in late-onset AD.
Although our knowledge about functions and regulation of mammalian LRP2s is extensive, insights into the properties of this receptor in other vertebrates may reveal important additional biological details.
Knowledge about functions can also inform future research seeking to develop new treatment approaches for NSI, and the possibility that treatment effectiveness may differ according to the functions present.
We envision that the wide application of ICF Core Sets for ADHD in research and clinical practice will lead to improved knowledge about functioning in ADHD, which in turn will lead to interventions that improve functioning and QoL for individuals with ADHD.
It may also reflect what previous authors have noted: namely, that for busy clinicians, time constraints and lack of knowledge about hand function tests may preclude the use of a standardised test of hand function [ 36, 37].
However, there is growing recognition that we should also use the wealth of accumulated knowledge about gene function to prioritize which genetic variations are analyzed for gene gene interactions and other complex effects.
Knowledge about splenic function is important, since patients with an absent spleen or decreased splenic function are at risk of developing severe infections with a high mortality rate.
Extensive knowledge about the function of this protein has come from the experimental use of the natural bacterial antibiotic rapamycin, which inhibits the activity of mTOR.
Standardized knowledge about genital function in adult female individuals with exstrophy-epispadias complex (EEC) is scarce.
The knowledge about brain function and its effects on learning have the potential to revolutionize teaching and learning.
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CEO of Professional Science Editing for Scientists @ prosciediting.com